Schedule a Demo

From CRIO to the World

Clinical research is global, and so are we. Today, we successfully serve client sites in almost 20 different geographies around the globe, collect data in at least 5 languages, and offer clients 24-hour live customer support. We have developed a global infrastructure and team that can service anyone, anywhere.

Sites all over the world have been successful with CRIO. We continue to build our global community of users, and together, we’re moving research forward.

Stipends Compliance Timezone Currency Language Voip/Texting Date Data Location Decimal Customer Support Data Consent


CRIO’s fully stacked software complies with the major global regulatory standards governing clinical research, including 21 CFR 11, EU Annex 11, GDPR, HIPAA, and China’s Personal Information Security Specification. Our rigorous policies and procedures satisfy local regulators. CRIO has been validated by outside experts and has third party attestations on 21 CFR 11, EU Annex 11 and GDPR compliance.

Time Zone

All time-stamps on the audit trail are displayed in the local time zone, as set by the site. The CRIO system automatically updates the stamps if the site changes the time zone.


With CRIO, sites can manage a financial portfolio spanning multiple currencies. Sites can specify the currency which the study sponsor uses to reimburse them, the currency in which their own vendors are paid, and the currency in which they pay their patients.


English and Portuguese language options are currently available. However, for electronic source data, sites can design questions and answers using their local language.


CRIO’s VOIP/ Texting feature is supported in major geographies. Support information and a complete country list is available here.


All dates in CRIO are expressed in the clinical research style format (05 Mar 2021).

Data Location

CRIO has developed a network of geographically dispersed servers to host our system with servers in the U.S., Canada, Germany, Australia, and coming soon, China. Data stays resident in that country, including off-site back-ups. PHI does not leave the particular country, satisfying local regulations that prohibit transmission of PHI to other jurisdictions.


Decimals in currencies are set to period or comma, per standard.

Customer Support

We offer 24 hour, 5 day-a-week live support.

Data Consent

Our system has settings that allow our sites to support local workflows. This includes a data consent workflow for the EU. Sites can keep track of patients’ consent to store their personal information in the recruiting database.


Sites can track patient stipend payments, regardless of currency.


“With CRIO, our HQ does all the study setup, regulatory and financial management, while our partners complete the eSource templates in Spanish. CRIO was so easy to use and took very little time to get up and running.”

- Juan Calderon

CEO, International Research Associates, LLC, US & Chile

“I use CRIO because there is no service like this in Brazil. An option of electronic source document in Portuguese with an automatic multi-currency financial platform is something that facilitates the clinical research activities in a complete and innovative way. With CRIO, we have been able to build out hubs across Brazil and bring research to underserved areas.”

- Keyla Deucher

CEO, BioServ SMO, Brazil

“We chose CRIO because we can customize it to suit our workflow, it is easy to use, and the billing is structured in a way that makes it economical for small clinics as well as large.”

- Krystyne Hitchcock

CEO, Affinity, Australia

“At Atlantia, we use CRIO as our CTMS for both our Chicago and our Cork, Ireland research sites. It is efficient and provides us with the exact information we need to run our studies seamlessly.”

- Shauna O’Sullivan

Recruiting and Marketing Manager, Atlantia, US & Ireland

“CRIO has been an enormous advantage for us. The system is easy to use and we have a great support from the team. This kind of electronic system is a great tool for studies. Web based access allows some staff to work from home – the savings are substantial.”

- Maude Bilodeau

Clinical Operation Advisor, Diex Recherche Research, French Canada

Learn More About CRIO


Give us a call: